NGP talks to Rino Rappuoli of Novartis about the breakthrough vaccines that could consign five deadly types of meningococcal disease to history.
The field of proteomics has made tremendous strides over the past decade, driven by advancements in mass spectrometry and bioinformatics. The increased sensitivity and throughput of mass spectrometers coupled with high-powered software algorithms have enabled the ability to identify thousands of proteins from very complex mixtures and perform quantitation between different sample types.
Multiplex, real-time PCR extends the power of PCR technology to provide quantitative data for multiple sequences of interest in a single-tube reaction. We examine the advantages of this technology, and describe its application in drug discovery.
With pipelines drying up and companies looking outside their traditional fields of inspiration to conjure up new innovation ideas, NGP though it would be a good idea to inspire you with some of the best – and worst – innovations and inventions of the 20th century.