Improved Flash Chromatography Products Launched

Pharmaceutical companies have a growing need to replenish their drug pipelines, as well as to work more productively and in a cost-effective manner. New developments in flash chromatography, a lab technique used by medicinal chemists to purify their synthesis products, allow scientists to pass along more purified material to later analyze the potential to interact with a disease target.

In 2008, Grace Davison launched GraceResolv High Resolution Flash Cartridges, containing its Davisil chromatographic silica gel as the adsorbent material. These cartridges have demonstrated superior performance in purity and loading capacity relative to competitive products.

These improvements in performance enable medicinal chemists in drug discovery to achieve purity targets for even complex samples. This allows the option of using smaller cartridges than would normally be required and reducing cartridge/solvent costs, or purifying larger amounts in the same size cartridge and improving throughput.

Grace has developed this new flash product line by drawing upon its strengths and greater than 80-year history in silica materials science. The GraceResolv Flash Cartridge complements other Grace offerings relevant to drug discovery, including its VisionHT UHPLC columns and Platinum HPLC columns. These products allow scientists in drug discovery to reduce runtimes significantly with better resolution, either using UHPLC systems or conventional HPLC, resulting from a 1.5 μm silica particle as well as unique hardware design. Unique selectivities offered by these products are good options for difficult separations.

How can Grace help you increase your throughput in drug discovery?